News & Stories

A research team led by Prof. HSING I-Ming, Professor of the Department of Chemical and Biological Engineering (CBE) at The Hong Kong University of Science and Technology (HKUST), in collaboration with Prof. ZHAI Yuanliang, Associate Professor of the Division of Life Science (LIFS), has successfully developed the world's first DNA-guided CRISPR-Cas system capable of programmable RNA targeting and cleavage.This breakthrough overturns the conventional CRISPR paradigm, which uses RNA as a guide to target DNA. The new system holds tremendous potential for clinical applications, opening new avenues for RNA-targeted therapies and diagnostics, including improved accuracy in rapid infectious disease testing and the advancement of antiviral treatments. The findings have been published in the international prestigious journal Nature Biotechnology.

A research team at The Hong Kong University of Science and Technology (HKUST) has achieved a major scientific breakthrough by developing the first artificial cilia system capable of replicating the fast, complex, three-dimensional motion of natural cilia found throughout the human body. The study, recently published in Nature titled “3D-printed low-voltage-driven ciliary hydrogel microactuators”, marks a significant advance in soft robotic materials and bio‑inspired micro‑engineering.Cilia—microscopic hair-like structures—play vital roles in clearing mucus from the lungs, circulating cerebrospinal fluid in the brain, and supporting reproductive processes. For decades, scientists have sought to recreate their sophisticated mechanics, but achieving realistic motion in engineered systems has remained a persistent challenge.

A research team from The Hong Kong University of Science and Technology (HKUST) has developed GrainBot, an AI-enabled toolkit that automatically extracts and quantifies multiple microstructural features from microscopy images. Designed to meet the growing need for data-driven and autonomous research workflows in materials science, the tool provides a systematic method for converting complex image information into quantitative data, thereby accelerating the discovery and development of next-generation materials.

Researchers at The Hong Kong University of Science and Technology (HKUST) have made a major breakthrough in producing perovskite solar cells. They developed a multi-source co-evaporation recipe that markedly enhances the crystal quality of vacuum-deposited perovskite films. The advance brings all vacuum-deposited single-junction perovskite cells as well as perovskite-on-silicon tandem solar cells closer to scalable production. This breakthrough has been reported in Nature Materials, in a paper entitled “Crystal-facet-directed all-vacuum-deposited perovskite solar cells”. 

Researchers at the School of Engineering of The Hong Kong University of Science and Technology (HKUST) have developed the world’s first Sub-Zero Celsius elastocaloric freezing device, capable of reaching temperatures as low as -12℃. This represents a significant milestone in expanding green solid-state elastocaloric refrigeration technology into the global freezing industry, offering a promising solution to combat climate change and accelerate low-carbon transformation of the global freezing market. The findings have recently been published in the international journal Nature, under the title “Sub-zero Celsius Elastocaloric Cooling via Low-transition-temperature Alloys”.

The Hong Kong University of Science and Technology (HKUST), in collaboration with the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), has launched the world's first Deep Ocean Omics (DOO) database (https://DeepOceanOmics.org/). As the largest platform of its kind, DOO integrates and analyzes multi-omics data from organisms thriving in the ocean's most extreme environments, alongside customized analytical tools to support cross-species comparative and evolutionary studies. By facilitating the utilization of deep-sea biological resources, the platform aims to advance scientific understanding of deep-sea biodiversity and ecosystems, and to foster global research and applications related to biological adaptation in extreme environments.

The Hong Kong University of Science and Technology (HKUST) and The Hong Kong and China Gas Company Limited (Towngas) today signed a Memorandum of Understanding on Strategic Cooperation to establish Hong Kong’s first hydrogen energy innovation platform. Leveraging global academic and industry expertise, the two parties will collaborate on areas such as technology commercialisation and related fields. This partnership aims to accelerate the development and broader application of hydrogen energy technologies, injecting fresh momentum into the nation’s dual-carbon strategy and the global transition to a low-carbon future.

A research team from the School of Engineering at The Hong Kong University of Science and Technology (HKUST) has achieved a major breakthrough in brain imaging by developing the world’s first technology to capture high-resolution images of the brain of awake experimental mice in a nearly non-invasive manner. By eliminating the need for anesthesia, this innovation enables scientists to study brain tissue in its fully functional state. The advancement promises deeper insights into human brain function in both healthy and diseased conditions, opening new frontiers in neuroscience research.