News & Stories
2021
News
HKUST Researchers Find Novel Way to Produce New Kind of Chiral Molecules Bringing New Hope for Drug Development
A research team from the Hong Kong University of Science and Technology (HKUST) has discovered a method that would allow the production of a new type of spherical molecules not easily obtainable before. Preliminary testing has also shown that such molecules – chiral tetraarylmethanes (CTAMs), display good deterrent effects against cancer cells such as those of cervical, lung, breast and colorectal, as well as the virus causing the Hand, Foot and Mouth disease (HFMD) and a type of coronavirus.
2022
News
HKUST & HKUMed Joint Study Reports Broadly Neutralizing Antibody That Protects Syrian Hamsters against SARS-CoV-2 Omicron Variants
Structural biologists at The Hong Kong University of Science and Technology (HKUST) together with researchers at the AIDS Institute, The University of Hong Kong (HKU), Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong (HKUMed) and the State Key Laboratory of Emerging Infectious Diseases, HKU have demonstrated that ZCB11, a broadly neutralising antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2. Critically, either prophylactic or therapeutic ZCB11 administration protects lung infection against Omicron viral challenge in golden Syrian hamsters.